CAUSES OF SHORT BOWEL SYNDROME WITH INTESTINAL FAILURE (SBS-IF)
SBS-IF is normally the result of an underlying condition requiring portions of your small intestine to be surgically removed.1–4
In less frequent cases, SBS-IF may already be present from birth as the result of a birth defect where portions of the small intestine are missing or damaged.1–4
CONDITIONS THAT LEAD TO INTESTINAL SURGERY
Conditions that may require significant portions of the small intestine to be surgically removed resulting in SBS-IF, include Crohn's disease, cancer and intestinal blood clots.1–4
TYPES OF INTESTINAL SURGERIES LEADING TO SBS-IF2
The small intestine is made up of three parts: the duodenum, jejunum and ileum. Surgeries resulting in the removal of different sections of the intestine can cause SBS-IF. Some intestinal surgeries that can result in SBS-IF are shown in figure 1.5
Long-term outcomes and symptoms of SBS-IF after surgery depend on the type of surgical procedure conducted and the length of remaining bowel.5 Multiple intestinal surgeries may result in SBS-IF and subsequent dependence on long-term parenteral support (PS).5
Multiple intestinal surgeries may result in SBS-IF and subsequent dependence on long-term parenteral support (PS).5
- Pironi L, et al. Clin Nutr. 2016;35(2):247–307.
- Hofstetter S, et al. Curr Med Res Opin. 2013;29(5):495–504.
- Kelly DG, et al. JPEN J Parenter Enteral Nutr. 2014;38(4):427–37.
- Howard L. Gastroenterology. 2006;130(2 Suppl 1):S52–9.
- Tappenden KA. JPEN J Parenter Enteral Nutr. 2014;38
Sections of the jejunum are removed.
The entire ileum is removed, and sometimes parts of the jejunum.
The entire large intestine and ileum are removed. Parts of the jejunum are also removed.
Date of preparation: April 2020 C-ANPROM/INT//7389