WHAT IS SBS-IF

Short bowel syndrome with intestinal failure (SBS-IF) is a highly complex, debilitating and life-threatening major organ failure in which patients are unable to absorb enough nutrients and fluids through the intestine. Patients have to be sustained on parenteral support (PS) – i.e. parenteral nutrition and/or intravenous fluids (PN/IV).1–3

SBS-IF normally occurs as a result of extensive surgical resection of the small intestine and is defined as a remaining small bowel length <200 cm. For patients with SBS-IF, the reduction in length and function of the small intestine results in chronic intestinal failure and long-term dependence on parenteral support.1–3

DEFINING INTESTINAL FAILURE

Intestinal failure is defined as the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or water and electrolytes, such that intravenous supplementation is required to maintain health, growth, and/or survival.1

Figure 1. Patients with SBS that develop IF are said to have SBS-IF.

Patients with a reduction of gut absorptive function who do not require intravenous supplementation to maintain health and/or growth are said to have intestinal insufficiency.1

Figure 1. Patients with SBS that develop IF are said to have SBS-IF.

Date of preparation: May 2020 C-ANPROM/INT//7387