Short Bowel Syndrome, or SBS, is a rare, life-threatening gastrointestinal disorder in which patients are unable to maintain nutrient and fluid balances with a normal diet.1–3 SBS generally occurs when a large portion of the small intestine has been removed by surgery for a variety of reasons, resulting in the loss of intestinal absorptive capacity but can also occur when the intestine loses the ability to function properly as a result of other disorders, including a rare congenital disorder.1–3
Patients with SBS are unable to maintain nutrient
and fluid balances with a normal diet.1–3 SBS occurs
when a large portion of the small intestine has been
removed by surgery, when there is a loss of function
as a result of other disorders, or due to a rare
This means that patients can no longer absorb enough fluids and nutrients from liquids and food they digest to maintain good health. This is known as malabsorption, and can put patients at risk of malnutrition, diarrhoea and dehydration.1–3
SBS can have a negative impact on a patient's quality of life because it restricts or alters their current lifestyles.1,4 However, with the right treatment and disease management, these restrictions can be attenuated.4
- Hofstetter S, Stern L, Willet J. Key issues in addressing the clinical and humanistic burden of short bowel syndrome in the US. Curr Med Res Opin 2013;29(5):495–504.
- Jeppesen PB. Spectrum of short bowel syndrome in adults: intestinal insufficiency to intestinal failure. JPEN J Parenter Enteral Nutr 2014;38(1 Suppl): 8S–13S.
- O'Keefe SJ, Buchman AL, Fishbein TM, et al. Short bowel syndrome and intestinal failure: consensus definitions and overview. Clin Gastroenterol Hepatol 2006;4(1):6–10.
- Kelly DG, Tappenden KA, Winkler MF. Short bowel syndrome: highlights of patient management, quality of life, and survival. JPEN J Parenter Enteral Nutr 2014;38(4):427–437.
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