Disease Management

There are a number of treatment options available to patients suffering from SBS, with primary management goals focusing on maintaining fluid, electrolyte and nutrient balances, as well as minimising disease complications.1,2

Patients who cannot meet their nutritional or fluid needs through oral intake require parenteral support; unfortunately long-term parenteral nutrition can lead to serious complications.3–5

The information in this section summarises the treatment options for patients with SBS with intestinal failure. Patients should always discuss the benefits and problems associated with each treatment option with their doctor. The doctor will provide advice on the most suitable treatments, and together, a decision can be made on an appropriate course of treatment.



  1. Buchman AL, Scolapio J, Fryer J. AGA technical review on short bowel syndrome and intestinal transplantation. Gastroenterology 2003;124(4):1111–34.
  2. Nightingale J, Woodward JM; Small Bowel and Nutrition Committee of the British Society of Gastroenterology. Guidelines for management of patients with a short bowel. Gut 2006;55(Suppl 4): iv 1–12.
  3. Jeppesen PB. Spectrum of short bowel syndrome in adults: intestinal insufficiency to intestinal failure. JPEN J Parenter Enteral Nutr 2014;38(1 Suppl):8S–13S.
  4. Hofstetter S, Stern L, Willet J. Key issues in addressing the clinical and humanistic burden of short bowel syndrome in the US. Curr Med Res Opin 2013;29(5):495–504.
  5. Mullady DK, O'Keefe SJ. Treatment of intestinal failure: home parenteral nutrition. Nat Clin Pract Gastroenterol Hepatol 2006;3(9):492–504.



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